California employment numbers improve as virus restrictions lift. California added , jobs in February as more than a quarter of a million people returned to the workforce. The Federal Emergency Management Agency plans to stop operating two mass vaccination sites in California next month, just days before the state makes everyone 16 and older eligible for the vaccine. The two sites shutting down are in Oakland and Los Angeles. The sites opened for eight-week pilot programs in February that will conclude April
South San Francisco, California
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The population of the region was 4,,, making it the largest bi-national conurbation shared between the United States and Mexico, the second-largest shared between the US and another country. The largest centers of the urban area maintain global city status  and as a whole the metropolitan region is host to 13 consulates from Asian, European, North American, Oceanian, and South American nations. Other key industries include military , biotech , and manufacturing. San Diego—Tijuana traces its European roots to when the land was explored by Portuguese explorers on behalf of imperial Spain. In it was mandated by the Spanish viceroy in Mexico City that safe ports be found, one of which would be San Diego Bay , for returning Spanish trade ships from Manila to Acapulco. Cabrillo first named San Diego , San Miguel. Initial expeditions by the west to the Californias were followed by pacification and conversion efforts by the Spanish Empire and the Catholic Church.
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With an estimated population of 1,,, it is the third-most populous city in California after Los Angeles and San Diego and the tenth-most populous in the United States. San Jose is the county seat of Santa Clara County , the most affluent county in California and one of the most affluent counties in the United States. San Jose is notable as a center of innovation , for its affluence ,    Mediterranean climate , and extremely high cost of living. Before the arrival of the Spanish , the area around San Jose was inhabited by the Tamien nation of the Ohlone peoples of California. After California achieved statehood two years later, San Jose became the state's first capital.